If iodine deficiency is severe and prolonged, the thyroid gland enlarges and forms a goiter. In a brain and spinal cord cell study, fucoidan reduced inflammation (blocking nitric oxide (NO) and prostaglandin E2 production). Join SelfHacked today and start the journey of improving your life. It also improved liver function tests and increased energy use at rest [29]. Although iodine is essential for strong health, you can have too much of a good thing. Kelp is also an excellent source of vanadium, used in clinical studies to lower glucose levels in individuals suffering from diabetes type 1 and 2. Fucoidan injections or fucoidan, when given in food, slowed tumor growth in mice. Fucoidan, a key component of seaweed, may fight cancer and stop tumor growth, based on both cell and animal models. T4 is not the active thyroid hormone; it must be converted into T3 in your body in order to exert its effects. They also have a huge bearing on your energy levels and maintenance of normal body temperature. Certain sea kelp, like sugar kelp, (Saccharina latissima) thrive in cold waters, off the coast of Connecticut and Maine. They may help reduce markers of heart disease, protect the cells (reducing oxidative stress), reduce inflammation in blood vessels, reduces high blood pressure, and decrease blood clotting [14]. Dandelion root, kelp, burdock root and turmeric aid in cleansing the body and protect against toxins. The mechanism by which kelp leads to a cholestatic syndrome has not yet been elucidated. SelfHacked does not endorse any specific product, service, or treatment. Minerals like iron, zinc phosphorus and potassium are also available in sea kelp, in smaller amounts. In another trial on 36 healthy people, kelp increased the levels of the hormone that stimulates the thyroid gland (TSH) [21]. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. These hormones help to control your metabolic rate, that is the rate at which your body burns calories. Dizziness, vertigo, nervousness, depression, headaches, decreased blood counts, anorexia, alopecia, abnormal liver function tests are few of the reported side effects of this drug. This list does not cover all possible side effects. Do not consider user experiences as medical advice. One of the other side effects of super-high doses of vitamin A is hair loss. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare providers because of something you have read on SelfHacked. Terms of Use Carlos spent 9 years in the laboratory investigating mineral transport in plants. Different kelp supplements exist with varying amounts of proteins and other nutrients. The potential health benefits of kelp are wide-ranging – it can fight iodine deficiency, help with diabetes, and prevent blood clots. The evidence for whether or not you can use resveratrol for weight loss remains inconclusive. Kelp, or brown algae, is found on the coasts of Korea and Japan. Side Effects of Taking Sea Kelp | … As a kid, he suffered from inflammation, brain fog, fatigue, digestive problems, anxiety, depression, and other issues that were poorly understood in both conventional and alternative medicine. Kelp has been an essential component of East Asian diets for centuries. Iodine, for example, already exists in abundance in our food, and although it’s important to our diet, too much of it may cause hyperthyroidism, Graves’ disease and even thyroid cancers. Kelp reduced the weight of liver and fat tissue, glucose, and fats (cholesterol and fatty acids) in the blood. He then started working as a freelancer, mainly in science writing, editing, and consulting. Your email address will not be published. Vanadium mimicked insulin in animal studies. However, the studies listed should not be interpreted as supportive of any health benefit. In a clinical trial on 24 people, dietary fucoidan prevented the formation of blood clots by increasing the production of two messengers (hydrogen peroxide and prostacyclins) in the blood vessels [32]. Never exceed this recommended dosage without consultation [80]. After 8 to 10 months of treatment, hepatitis C virus (HCV) levels in the blood significantly decreased [46]. The kelp plant is made up of three parts: the blade (the leaf-like structure), the stipe (the ste… As a huge source of iodine, kelp supplements may interfere with thyroid replacement therapies. In another study in cells and mice, fucoidan stopped the growth and spread of lung cancer cells by blocking growth pathways (Akt–mTOR and NF-kB) [45, 44]. Read more: Does Sea Salt Have Iodine in It? Users regarded kelp as an effective agent for weight loss and an essential ingredient in energy-boosting juices. It should not be Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the A study of 15 postmenopausal women, 10 of whom were breast cancer survivors, looked at the effects of brown seaweed supplementation over a 3-month period (alternating with placebo). It grows in shallow, nutrient-rich saltwater, near coastal fronts around the world. A 2-tablespoon serving offers 6 percent recommended daily dose of vitamin K and 1 percent of the recommended daily dose of vitamins B5 and E. Kelp, which is sometimes consumed in the form of kelp supplements, can have an adverse effect on people with hypothyroidism due to its high iodine content. What Food Does Your Body Need To Stay Healthy? Just like plants on land, sea kelp requires light from the sun to carry out photosynthesis and prefers growing in bodies of water that are rich in nutrients. ", American Thyroid Association: "American Thyroid Association (ATA) Issues Statement on the Potential Risks of Excess Iodine Ingestion and Exposure", Analytical Methods: Advancing Methods and Applications: "SI Traceable Determination of Arsenic Species in Kelp (Thallus laminariae)", Analytical and Bioanalytical Chemistry: “Development of a Kelp Powder (Thallus laminariae) Standard Reference Material", Environmental Science and Pollution Research International: "Comparative Study on Metal Biosorption by Two Macroalgae in Saline Waters: Single and Ternary Systems”, PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. Fucoidan reduced the growth of leukemia cells and killed 2 out of 4 lines tested in a study. Dried seaweed may have high heavy metal content, such as cadmium (Cd). You can take kelp as food, pill, powder, or tincture. Excessive amounts of iodine, similar to deficiencies, can alter thyroid hormones released and impair overall thyroid function [92, 74, 93, 94]. Fucoidan given to aged female mice increased bone density and weight suggesting that fucoidan may play a role in treating age-related bone loss [65, 66, 67, 68]. This later developed into low thyroid activity (hypothyroidism) caused by the excess iodine in the seaweed [73, 74, 75, 76]. Importantly, the FDA-recommended dosage for daily intake of iodine is 225 μg. The material appearing on LIVESTRONG.COM is for educational use only. Only in very few situations can it have adverse effects. A 45-year-old woman with no history of thyroid disease experienced an extended period of thyroid hyperactivity (hyperthyroidism) shortly after beginning a kelp-containing diet. Kelp for Dogs (FTC Disclosure: If you make a purchase via a link on this page, I may receive a small commission, at no added cost to you.Overview. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. In a cell study, 5 organic brown seaweed (kelp) extracts blocked an important enzyme that may contribute to high blood pressure (Angiotensin-converting Enzyme, ACE). Most T4 to T3 con… Your email address will not be published. These cultures … If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [email protected]. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists. Their reviews do not represent the opinions of SelfHacked. Diarrhea may also interfere with your body's ability to absorb essential electrolytes, such as potassium and sodium, and may increase your risk of becoming dehydrated. From the excessive iodine, the thyroid glands swelled, leading to hypothyroidism and reducing liver function [78, 79, 74]. According to the USDA, sea kelp contains trace amounts of vitamins like vitamin B5, vitamin C and vitamin E, as well as vitamin K, which is an essential vitamin for the body's blood clotting process. Others like Ecklonia radiata are native to the waters surrounding western Australia. Kelp is a seaweed that belongs to the brown algae family Laminaiaceae. The high iodine content in kelp supports the production of thyroid hormones T3 and T4. , The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. The reaction included breathing difficulty, nausea, and dangerously low blood pressure. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Levels of other toxic heavy metals, such as arsenic, lead, aluminum, and mercury in Korean seaweed were determined to be very low and not a health threat [82, 83, 84]. Kelp may also improve diabetes, reduce blood clots, and even help fight hepatitis C and breast cancer [1]. According to an August 2017 study published in Analytical Methods: Advancing Methods and Applications, high levels of arsenic are toxic and carcinogenic in nature. is a clickable link to peer-reviewed scientific studies. advertisements are served by third party advertising companies. Required fields are marked *. Dosage. All of our content is written by scientists and people with a strong science background. Below, we will discuss some preliminary research on kelp’s potential anticancer. Don't worry about getting too much Iodine in your diet. A plus sign next to the number “[1+, 2+, etc...]” means that the information is found within the full scientific study rather than the abstract. Kelp can have many therapeutic and nutritional benefits, as it is a Carlos is passionate about learning the mechanisms behind biological processes and communicating science to both academic and non-academic audiences. It originates from a marine bacterium (via gene transfer) living on the surface of some sea algae species [95]. Chlorella and spirulina are types of blue-green algae often consumed in supplement form. Fucoxanthin, a pigment from seaweed, produced these effects [12, 30]. Bladderwrack Reviews [Fucus vesiculosus, related to Kelp] Bladderwrack (Bladder Wrack, Fucus vesiculosus) is a rockweed or seaweed having forked, brownish-green branches with gas-filled bladders. Oral vanadium supplements (150 to 300 mg daily) given to 14 type 1 diabetic patients (longitudinal study) for 30 months decreased fasting blood sugar levels by over 30%. Kelp has potential cancer-fighting properties. Kelp has been associated with adverse reactions with levothyroxine and other thyroid replacements leading to hyperthyroidism.4 To our knowledge, kelp has not been shown to have a significant adverse effect on the liver. Christabel Lobo is a freelance health and wellness writer currently based in Mysore, south India’s yoga capital. Read on to find out more. Despite the positive laboratory findings, these results did not lead to significant clinical improvements [46, 47]. In fact, this diet introduced kelp into different regions across the world. LIVESTRONG.com may earn compensation through affiliate links in this story. If you want to use it as a supportive measure, talk to your doctor to avoid any unexpected interactions. In tissues with low blood supply, fucoidan decreased cell death proteins (including MAPK, JNK, and caspase-3) and harmful compounds (reactive oxygen species) [35]. A 2-tablespoon serving of raw sea kelp has just 4 calories, 0.17 grams of protein, 0.96 grams of carbohydrates and less than 0.1 grams of both fat and sugar. Privacy Policy Fucoidan infusion decreased clotting in bleeding in rats. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Read more: Side Effects of Iodine Supplements. According to the Connecticut Department of Agriculture, seaweeds like sea kelp are able to extract nutrients, both inorganic and organic, from seawater, making themselves naturally nutrient-rich. Fucoxanthin, a pigment found in brown seaweed, may also boost weight loss [8, 9, 10, 11, 12]. Powdered seaweed pills reduced sugar levels in a study of 20 subjects with type 2 diabetes (RCT), taken daily for 4 weeks. Previous laminaria tent procedures possibly caused this sensitivity [91]. Nutrients from seaweed carry potential health benefits. any of the products or services that are advertised on the web site. Kelp is a form of large brown sea algae. Sea kelp is generally safe, and side effects related to its consumption are rare. Fucoidan blocked the growth of the herpes simplex virus type 1 (HSV-1) in infected mice. We do not aim to diagnose, treat, cure or prevent any illness or disease. Drug Interactions Additionally, users with histories of thyroid issues claimed that the source of iodine present in kelp and its supplements worked better than previously prescribed iodine pills, even improving metabolism. Different types of kelp are used, including winged kelp, laminarin, and fingered tangle. Increased risk of infections – both viral and bacterial. 2020 Theoretically, one could eat too much liver and get vitamin A toxicity, but this would take eating repeated doses in very large quantities. In one study (longitudinal), 171 late second-trimester abortions were performed using Laminaria (cervical preparation). In the cases of inflammation, oxidative damage, herpes, brain protection, bone health, and blood pressure and fats, only animal and cell-based studies have been carried out. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. He strongly believes that scientific literacy is crucial to maintain a healthy lifestyle and avoid falling for scams. Certain kelp supplement users complained of gaining weight and experiencing depression after long periods of use. Kelp Extract Side Effects. It improved thyroid function in a study of 7 patients with severe motor and intellectual disabilities and hypothyroidism due to iodine deficiency. Though kelp may look like a plant, it is actually a form of sea algae. We understand that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. These are being grown and harvested as a new sea vegetable. Fucoidan also increased the growth of new vessels, improving communication with bones [63, 64]. Patients were given 1 to 2 grams of powdered kelp daily, and this treatment restored thyroid function, increasing the concentration of iodine in the urine [20]. It Helps in Maintaining Required Lipid Profile. This caused iodine toxicity, impairing thyroid function, and possible arsenic poisoning (present in the patient’s urine) that caused the symptoms [80, 74]. Im feeding her raw Kangaroo st present as she has been itching on beef and chichen. Be sure to discuss with your doctor if it may be helpful in your case and how you should take it. In nature, different kelp species (such as Laminaria digitata, Laminaria Hyperborea, Saccharina latissima, Alaria esculenta) that carry more proteins may contain less long-chain carbohydrates (such as fucoidan), and vice-versa [95, 90]. Side Effects & Safety Alfalfa leaves are POSSIBLY SAFE for most adults. Align your health hacks with your genes for optimal health & cognitive function. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. The sticks cause the release of prostaglandins, which act as hormones that help initiate womb contractions [15, 16]. Can Kelp cause Liver Damage? Kelp is an excellent source of iodine, potassium, magnesium, iron, and calcium [2]. Only one had serious complications (no contractions during delivery) and 9 required additional safety measures [17, 15, 18]. The rats also had less inflammation around the area of swelling, moved easier, and had better memory retention after fucoidan treatment [33]. Iodine Overdose. Intake of more than 2000 mcg of kelp a day may also lead to interference of normal thyroid functions and other harmful A 1% or 5% fucoidan (from kelp) diet reduced fat in mice that were fed a high-fat diet over 12 weeks. Authors of the February 2018 study published in Analytical and Bioanalytical Chemistry explain that one of the dietary kelp side effects is toxicosis due to its levels of arsenic, resulting in diarrhea, nausea and overall body weakness. However, there are better and safer methods for inducing labor or abortion. In a Japanese clinical trial on 13 people, eating 15-30 grams of kelp per day suppressed thyroid function, resulting in low thyroid hormone levels [22]. She graduated summa cum laude from Fresno State with a Bachelors of Science in Animal Sciences and Pre-Veterinary Medicine, concentrating on animal agriculture and dairy production. Weigh chlorella and spirulina side effects against possible benefits. Save my name, email, and website in this browser for the next time I comment. One of the kelp supplement side effects therefore is loose bowel movements or even diarrhea. Sea kelp contains relatively few calories. diagnosis or treatment. Fucoidan from kelp may kill cancer cells and stop their growth [5]. Giant kelp, sugarwack, southern kelp, and bull kelp are a few different varieties of kelp. Your thyroid gland produces two main hormones: T4 (also called thyroxine) and T3 (also called triiodothyronine). Mice given fucoidan had better survival rates. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. You must stop taking iodine, once you experience the side effects. Sea kelp is high in minerals like sodium, which, according to U.S. National Library of Medicine, is responsible for maintaining the body's fluid balance. Intake may also cause side effects including lip and face swelling, bleeding and bruising, fever, joint pain, lymph node enlargement in sensitive people. Still, another cellular study (initiated in response to the case of severe side effects) found detectable arsenic levels in 8 out of 9 tested kelp supplements. Concerns about liver damage from green tea extract have prompted France and Spain to remove a weight-loss product containing the ingredient from the market, according to the USP. Kelp supplements have been linked to autoimmune disorders that cause red blood cells and blood clotting factors to become defective and attacked by the body’s immune system due to the possible presence of toxic metal (arsenic) [86, 87, 88, 89]. However, kelp should not be consumed in large amounts through the implementation of wrong methods as it may lead to adverse effects. Kelp is the most nutritious of all sea vegetables. It is rich in minerals and trace elements and has a nourishing and tonic effect on all of the body's systems. Laminaria sticks can mechanically assist in terminating pregnancy from the first to the late second trimester of pregnancy. The opinions expressed in this section are solely those of kelp users, who may or may not have medical or scientific training. The LIVESTRONG Foundation and LIVESTRONG.COM do not endorse It decreased fasting and post-meal blood sugar levels and serum lipid (fatty acid) levels. Kelp is also high in arsenic, a carcinogenic compound. Kelp also contains a complex long-chain carbohydrate (polysaccharide) called fucoidan. It also protected from toxins, helping the cells avoid death (via hydrogen peroxide and caspase-3) [59, 60, 61, 62]. In another study, fucoidan injections in mice led to enhanced cell survival and function in tissues with low blood supply (ischemia) [34, 35, 36, 37]. The blood tests also present a decrease in alanine aminotransferase levels. Kelp supplements often contain several thousand times the daily recommended limit of iodine, which can sometimes do more harm than good. The liver is an important organ that performs many vital roles in the body. Of the 10 extracts, 4 experienced decreased blood pressure after both a single dose and routine use [69]. A June 2016 study published in Environmental Science and Pollution Research International found that water with high levels of mercury can be remediated by kelp's mercury absorption abilities. Fucoidan improved animal behavior, reduced harmful compounds (TNF-alpha), prevented neuron loss, and protected the cells from damage (reducing reactive oxygen species) that can cause neurodegeneration [48, 49, 50]. A 39-year-old woman presented with a case of hyperthyroidism after drinking a kelp-containing herbal tea. One standard serving of Grassland Nutrition Liver/Kelp taken daily is 3 grams, which works out to 21 grams per week, which roughly works out to a standard serving of 3 oz of liver per week. The tea consumption led to the formation of a goiter, an abnormal enlargement of the thyroid gland [77, 74]. Levels of arsenic were higher than the FDA tolerance level for certain food products. Side effects may include nausea and stomach pain, runny nose, headache, metallic taste, and diarrhea. Vanadium also decreased cholesterol levels. The antioxidant properties of fucoidan (from kelp) were confirmed in a cell study that tested its 2 major components, sulfate and fucose. While there are many purported benefits of eating kelp, there are some sea kelp side effects to be aware of, including its high iodine and arsenic content. However, only approximately one percent of the arsenic in sea kelp is the toxic inorganic form, while close to 95 percent of the arsenic present is arsenosugar, a harmless organic compound. Similarly, a 40-year-old woman developed liver damage (hepatotoxicity) after drinking an herbal tea that contained kelp 3 times a day over 2 months. Fucoidan reduced all important actors in the inflammatory cascade in cell studies. This site uses Akismet to reduce spam. Since my weight retention issues seem to be related to my liver function, a nice side effect of this (in addition to clearer skin, abundant energy, and a multitude of other benefits) was that my weight naturally balanced out. Yale School of Forestry and Environmental Studies, Watch Out for the Sodium in Seaweed Salad, Analytical Methods: Advancing Methods and Applications, Environmental Science and Pollution Research International, Yale School of Forestry and Environmental Studies: "As Oceans Warm, the World’s Kelp Forests Begin to Disappear”, National Ocean Service: "What Is a Kelp Forest? Selfhacked LLC does not provide medical advice, diagnosis, or treatment. . Obviously this is far more than the RDA and can result in cirrhosis of the liver. Supplement Use & Side Effects, Ripen the cervix with synthetic prostaglandins, Give intravenous Pitocin (synthetic oxytocin). There are around 30 varieties of kelp. SelfDecode’s personalized DNA reports can tell you which vitamins and mineral deficiencies you’re susceptible to, and which foods to consume to prevent these deficiencies. Not Suitable for People with Heart Diseases: Large intake of cod liver oil will lead to heart failure, … Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Two women experienced anaphylactic shock, an extremely severe and possibly fatal allergic reaction when Laminaria (a type of kelp) sticks were used to terminate a pregnancy. It also may be capable of preventing DNA damage. It caused no major side effects, with the exception of mild diarrhea at the beginning of the treatment period [27, 10]. It also contains kelp to give this supplement an iodine boost. Increased risk of some types of cancer, including thyroid cancer. The following purported benefits are only supported by limited, low-quality clinical studies and some animal research. It also partially improved bone growth in rabbits with defects in skull formation [63]. Hi Daryll, I have a F German Sheperd pup 13 wks. Sea kelp is a variety of seaweed grown underwater in salty coastal environments. Kelp is eaten as food in Japan, Alaska, and Hawaii. All in all, the evidence suggests that appropriate kelp doses may improve iodine deficiency and thyroid function. Fucoidan also blocked inflammatory proteins (cytokines IL-1β and TNF-alpha) and the inflammation pathway (reducing NF-kβ and p38 MAPK) [6, 51, 49, 52, 53, 54, 55]. Use of this web site constitutes acceptance of the LIVESTRONG.COM Kelp is a great source of vanadium. Some side effects may be very serious. Kelp is a good source of folic acid (one of the B vitamins), as well as many other vitamins. Others complained of excessive sweating and mucus formation after taking kelp-based supplements. Another type of seaweed – Gracilaria changii – is rich in fiber content and essential amino acids (the building blocks of proteins) [4, 3]. Mice fed fats from seaweed had increased markers of weight loss in fat tissue. Seaweed decreased an important marker of breast cancer recurrence by half (receptor uPAR) after 4 weeks [38, 39]. In another trial on 65 people, polyphenols extracted from two different kelp species lowered blood sugar, insulin resistance, and inflammatory markers [25]. According to the Yale School of Forestry and Environmental Studies, some forms of kelp are brown in color and can grow up to 100 feet in length. In a rabbit model, fucoidan helped create new vessels, essential for communication with bones and bone repair. SelfHacked © 2013 – 2020 All Rights Reserved. Fucoidan is responsible for several potential effects of kelp, including antioxidant, anti-inflammatory, and cancer fighting [5, 6, 7]. Always consult your doctor before supplementing and let them know about all drugs and supplements you are using or considering. In one study with diabetic mice, a vanadium-based compound reduced blood sugar levels and diabetic symptoms (such as thirst, hunger, and weight loss), with no side effects [28]. Supplement/Herb/Nutrient-drug interactions can be dangerous and, in rare cases, even life-threatening. Years ago I used to purchase Liv-Guard from Nature's Sunshine, and it made a tremendous difference in my energy level. A 2-tablespoon serving contains 23 milligrams of sodium, or 1 percent of the recommended daily dose, as well as 17 milligrams of calcium and 12 milligrams of magnesium. Leaf Group Ltd. If you are a pregnant or nursing female, you need more. Of these, 26 were deemed to potentially lead to iodine intake above the accepted level [90]. In a study (cell), seaweed extracts (including kelp) protected brain cells from death in cell models of Parkinson’s disease and improved cell survival. It can interfere with … Some even complained of developing the dependency on the supplements for thyroid function, due to the resulting iodine imbalance. Claudia is an expert at intuitive eating, nutrition science, and removing diets from your life. Newer research is taking a look at gotu kola’s effect on liver and kidney toxicity. Contact your doctor or pharmacist if you notice any other side effects. and Do not under any circumstances attempt to replace conventional cancer therapies with kelp, its active compounds, or any other supplements. Inducing Labor and Facilitating Abortion Procedures, Animal and Cell Research (Lack of Evidence), 4) Allergic Reactions to Laminaria Sticks. Start your journey to optimal health with SelfDecode today. Depending on the circumstances, doctors may [19]: Kelp has a high iodine content (200 to 400 µg). Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.. Stop taking paliperidone and call your doctor at once if you have any of these signs of a serious movement disorder: Cadmium can cause toxicity in the body [81].

kelp side effects liver

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